Metalloantimalarials: synthesis and characterization of a novel agent possessing activity against Plasmodium falciparum.

نویسندگان

  • Joseph A Ocheskey
  • Scott E Harpstrite
  • Anna Oksman
  • Daniel E Goldberg
  • Vijay Sharma
چکیده

The synthesis, characterization, and antimalarial potency of an amine-phenol complex of gallium(III), [{1,12-bis(2-hydroxy-3-methoxy-5-(quinolin-3-yl)-benzyl)-1,5,8,12-tetraazadodecane}-gallium(III)]+, [Ga-3-M-5-Quadd]+ (7) is described; a novel agent that targets Plasmodium falciparum strains.

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عنوان ژورنال:
  • Chemical communications

دوره 12  شماره 

صفحات  -

تاریخ انتشار 2005